Acute management of anaphylaxis guidelines (2023)

ASCIA HP Guidelines Acute Management Anaphylaxis 2023336.51 KB

This document has been developed by ASCIA, the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand. ASCIA information is based on published literature and expert review, is not influenced by commercial organisations and is not intended to replace medical advice.

For patient or carer support contact Allergy & Anaphylaxis Australia or Allergy New Zealand.

ASCIA guidelines for the acute management of severe allergic reactions (anaphylaxis) are intended for medical practitioners, nurses and other health professionals who provide first responder emergency care. Appendix A includes additional information for health professionals working in emergency departments, ambulance services, and rural or regional areas, who provide emergency care.


  1. Definition and clinical diagnostic criteria for anaphylaxis
  2. Signs and symptoms of allergic reactions
  3. Immediate actions for anaphylaxis
  4. Anaphylaxis triggers and reaction times
  5. Adrenaline (epinephrine) administration and dosages
  6. Management of anaphylaxis in pregnancy and infants
  7. Positioning of patients with anaphylaxis
  8. Equipment required for acute management of anaphylaxis
  9. Supportive management and additional measures
  10. Actions after administration of adrenaline

Appendix A: Advanced Acute Management of Anaphylaxis
Appendix B: Acknowledgements

1. Definition and clinical diagnostic criteria for anaphylaxis

ASCIA defines anaphylaxis as:

  • Any acute onset illness with typical skin features (urticarial rash or erythema/flushing, and/or angioedema), plus involvement of respiratory and/or cardiovascular and/or persistent severe gastrointestinal symptoms; or
  • Any acute onset of hypotension or bronchospasm or upper airway obstruction where anaphylaxis is considered possible, even if typical skin features are not present.

The ASCIA definition is consistent with the following criteria published in the World Allergy Organisation Anaphylaxis Guidance Position Paper 2020.

Anaphylaxis is highly likely when any one of the following two criteria are fulfilled:
Criteria 1.
Acute onset of an illness (minutes to several hours) with simultaneous involvement of the skin, mucosal tissue, or both (e.g. generalized hives, pruritus or flushing, swollen lips-tongue-uvula), and at least one of the following:
a) Respiratory compromise (e.g. dyspnea, wheeze-bronchospasm, stridor, reduced peak expiratory flow, hypoxemia).
b) Reduced blood pressure or associated symptoms of end-organ dysfunction (e.g. hypotonia [collapse], syncope, incontinence).
c) Severe gastrointestinal symptoms (e.g. severe crampy abdominal pain, repetitive vomiting), especially after exposure to non-food allergens.
Criteria 2.
Acute onset of hypotension or bronchospasm or laryngeal involvement after exposure to a known or highly probable allergen for that patient (minutes to several hours), even in the absence of typical skin involvement.

2. Signs and symptoms of allergic reactions

Mild or moderate reactions (may not always occur before anaphylaxis):

  • Swelling of lips, face, eyes
  • Hives or welts
  • Tingling mouth
  • Abdominal pain, vomiting - these are signs of anaphylaxis for insect sting or injected drug (medication) allergy

Anaphylaxis – Indicated by any one of the following signs:

  • Difficult or noisy breathing
  • Swelling of tongue
  • Swelling or tightness in throat
  • Difficulty talking or hoarse voice
  • Wheeze or persistent cough - unlike the cough in asthma, the onset of coughing during anaphylaxis is usually sudden
  • Persistent dizziness or collapse
  • Pale and floppy (young children)
  • Abdominal pain, vomiting - for insect stings or injected drug (medication) allergy.

3. Immediate actions for anaphylaxis

  1. Remove allergen (if still present), stay with person, call for assistance and locate adrenaline injector.
    1. LAY PERSON FLAT - do NOT allow them to stand or walk
    • If unconscious or pregnant, place in recovery position - on left side if pregnant, as shown below
    • If breathing is difficult allow them to sit with legs outstretched
    • Hold young children flat, not uprightAcute management of anaphylaxis guidelines (2)
  2. GIVE ADRENALINE INJECTOR -Give intramuscular injection (IMI) adrenaline into outer mid-thigh without delay using an adrenaline autoinjector if available OR adrenaline ampoule/syringe. Adrenaline (epinephrine)is the first line treatment for anaphylaxis
  3. Give oxygen (if available).
  4. Phone ambulance- 000 (AU) or 111 (NZ) to transport patient if not already in a hospital setting.
  5. Phone family/emergency contact.
  6. Further adrenaline may be given if no response after 5 minutes.


  7. Transfer person to hospital for at least 4 hours of observation.
  8. Commence CPRat any time if person is unresponsive and not breathing normally.

ALWAYS give adrenaline FIRST, then asthma reliever if someone with known asthma and allergy to food, insects or medication has SUDDEN BREATHING DIFFICULTY (including wheeze, persistent cough or hoarse voice) even if there are no skin symptoms.

Note: If adrenaline is accidently injected (e.g. into a thumb) phone your local poisons information centre. Continue to follow this action plan for the person with the allergic reaction.

(Video) Diagnosis and management of acute anaphylaxis

4. Anaphylaxis triggers and reaction times

The most common triggers of anaphylaxis are foods, insect stings and drugs (medications). Less common triggers include latex, tick bites, exercise (with or without food), cold temperatures, radiocontrast agents, immunisation (rare) and unidentified (idiopathic).

Anaphylaxis usually occurs within one to two hours of ingestion in food allergy. The onset of a reaction may occur rapidly (within 30 minutes) or may be delayed several hours (for example, in mammalian meat allergy and food dependent exercise induced anaphylaxis, where symptoms usually occur during exercise).

Anaphylaxis to stings and injected medications (including radiocontrast agents and vaccines) usually occurs within 5-30 minutes but may be delayed. Anaphylaxis to oral medications can also occur but is less common than to injected medications.

5. Adrenaline administration and dosages

Adrenaline is the first line treatment for anaphylaxis and acts to reduce airway mucosal oedema, induce bronchodilation, induce vasoconstriction and increase strength of cardiac contraction.

Give INTRAMUSCULAR INJECTION (IMI) OF ADRENALINE (1:1000) into outer mid-thigh (0.01mg per kg up to 0.5mg per dose) without delay using an adrenaline autoinjector if available OR adrenaline ampoule and syringe, as shown in the table below:

Adrenaline (epinephrine) dose chart

Age (years)

Weight (kg)

Volume (mL) of adrenaline 1:1,000 ampoules*

Adrenaline injectordevices (for use instead of ampoules)



0.1 mL

Not available



0.1 mL

7.5-20 kg (~<5yrs)

150 microgram device**



0.15 mL



0.2 mL



0.3 mL

>20 kg (~>5yrs)

300 microgram device***



0.4 mL

~>12 and adults


0.5 mL

>50 kg (~12 years)

300 microgram or 500 microgram**** device

*Adrenaline 1:1,000 ampoules contain 1mg adrenaline per 1mL

**EpiPen® Jr andAnapen® Junior 150 are examples of 150 microgram (0.15 mg) devices.

***EpiPen® and Anapen® 300 are examples of 300 microgram (0.3 mg) devices.

****Anapen® 500 is an example of a 500 microgram (0.5 mg) device.

The adrenaline injector devices listed above are available in Australia and listed on the Pharmaceutical Benefits Scheme (PBS).

EpiPen® and EpiPen® Jr are available in New Zealand (Pharmac listed since 1 February 2023).


  • If multiple doses are required for a severe reaction (e.g. 2-3 doses administered at 5 minute intervals), consider adrenaline infusion if skills and equipment are available.
  • For emergency treatment of anaphylaxis, ampoules of adrenaline 1:1,000 should be used for both IM doses and infusion if required (adrenaline 1:10,000 should not be used).

6. Management of anaphylaxis in pregnancy and infants

Management of anaphylaxis in pregnancy

Management of anaphylaxis in pregnant women is the same as for non-pregnant women. Adrenaline should be the first line treatment for anaphylaxis in pregnancy, and prompt administration of adrenaline (1:1,000 IM adrenaline 0.01mg per kg up to 0.5mg per dose) should not be withheld due to a fear of causing reduced placental perfusion. The left lateral position is recommended, as shown below. For more information go

Management of anaphylaxis in infants

Whilst 10-20kg was the previous weight guide for a 150 microgram adrenaline injector device, a 150 microgram device may now also be prescribed for an infant weighting 7.5-10 kg by health professionals who have made a considered assessment. Use of a 150 microgram device for treatment of infants weighing 7.5 kg or more poses less risk, particularly when used without medical training, than use of an adrenaline ampoule and syringe.

Infants with anaphylaxis may retain pallor despite 2-3 doses of adrenaline, and this can resolve without further doses. More than 2-3 doses of adrenaline in infants may cause hypertension and tachycardia, which is often misinterpreted as an ongoing cardiovascular compromise or anaphylaxis. Blood pressure measurement can provide a guide to the effectiveness of treatment, to check if additional doses of adrenaline are required. The correct way to hold an infant is flat, as shown below.

7. Positioning of patients with anaphylaxis

  • Fatality can occur within minutes if a patient stands, walks or sits suddenly.
  • Patients must NOT walk or stand, even if they appear to have recovered.
    A wheelchair, stretcher or trolley bed should be used to transfer the patient:
    - To the ambulance and from the ambulance to the treatment room bed.
    - From the treatment room bed to and from the toilet.
    Acute management of anaphylaxis guidelines (3)
  • Laying the patient flat (see image above) will improve venous blood return to the heart. By contrast, placing the patient in an upright position (standing or walking) can impair blood returning to the heart, resulting in insufficient blood for the heart to circulate and low blood pressure. This means that patients should not stand or walk, and this includes not being showered.
  • If unconscious, vomiting or pregnant, lay the patient on their side in the recovery position.
  • The left lateral (recovery) position is recommended for patients who are pregnant (see image above). This reduces the risk of compression of the inferior vena cava by the pregnant uterus and improves venous return to the heart.


  • Patients with mostly respiratory symptoms may prefer to sit with their legs outstretched in front of them (see image above), which may help support breathing and improve ventilation. They should not sit on a chair as this may trigger hypotension. Monitor closely and immediately lay the patient flat if there is any alteration in conscious state or drop in blood pressure.

  • The correct way to hold an infant or young child is flat (see image above),not upright nor over a shoulder.
  • Do not allow the patient to stand or walk until they are haemodynamically stable, which is usually a minimum of 1 hour after 1 dose of adrenaline and 4 hours if more than 1 dose of adrenaline.

8. Equipment required for acute management of anaphylaxis

The equipment on your emergency trolley should include:
• Adrenaline 1:1,000 (consider adrenaline injector availability for initial administration by nursing staff)
• 1mL syringes; 22-25 G needles (25mm length) are recommended for IM injections for all ages* (consistent with Australian Immunisation Handbook).*Exceptions are preterm/very small infants (23-25G needle length 16mm) and very large adults (22-25G and needle length up to 38mm).
• Oxygen, airway equipment, including rebreather oxygen masks, nebuliser masks and suction
• Defibrillator
• Manual blood pressure cuff
• IV access equipment (including large bore cannulae)
• At least 3 litres of normal saline
• A hands-free phone in resuscitation room, to allow health care providers in remote locations to receive instructions by phone whilst keeping hands free for resuscitation.

9. Supportive management and additional measures - see Appendix A for additional information

Supportive management - when skills and equipment are available:

  • Check pulse, blood pressure, ECG, pulse oximetry, conscious state.
  • Give high flow oxygen if available and airway support if needed.
  • Obtain IV access in adults and tachycardic and/or hypotensive children. The first sign of cardiovascular compromise in children is ongoing tachycardia. Hypotension can occur later, when it can then be difficult to get IV access, resulting in a significantly prolonged recovery process.
  • If hypotensive, give IV normal saline 20mL/kg rapidly and consider additional wide bore IV access.

Additional measures - IV adrenaline infusion in clinical setting:

If there is an inadequate response after 2-3 adrenaline doses, or deterioration of the patient, start IV adrenaline infusion, given by staff trained in its use or in liaison with an emergency specialist.

IV adrenaline infusions should be used with a dedicated line, infusion pump and anti-reflux valves wherever possible.

CAUTION: IV boluses of adrenaline are NOT recommended without specialised training as they may increase the risk of cardiac arrhythmia.

Additional measures to consider if IV adrenaline infusion is ineffective

For upper airway obstruction

  • Nebulised adrenaline (5mL e.g. 5 ampoules of 1:1000).
  • Consider need for advanced airway management if skills and equipment are available.

For persistent hypotension/ shock

  • Give normal saline (maximum of 50mL/kg in first 30 minutes).
  • Glucagon
  • In adults, selective vasoconstrictors only after advice from an emergency medicine/critical care specialist.

For persistent wheeze

Bronchodilators: Salbutamol 8-12 puffs of 100microgram (spacer) or 5mg (nebuliser).

Note: Bronchodilators must not be used as first line medication for anaphylaxis as they do not prevent or relieve upper airway obstruction, hypotension or shock.

Corticosteroids: Oral prednisolone 1 mg/kg (maximum of 50 mg) or intravenous hydrocortisone 5 mg/kg (maximum of 200 mg).

Note: Steroids must not be used as a first line medication in place of adrenaline as the benefit of corticosteroids in anaphylaxis is unproven.

Antihistamineshave no role in treating or preventing respiratory or cardiovascular symptoms of anaphylaxis.Do not use oral sedating antihistamines as side effects (drowsiness or lethargy) may mimic some signs of anaphylaxis.Injectable promethazine should not be used in anaphylaxis as it can worsen hypotension and cause muscle necrosis.

10. Actions after administration of adrenaline

Observation of patient for at least 4 hours after last dose of adrenaline

Relapse, protracted and/or biphasic reactions may occur and overnight observation is strongly recommended if they:

  • Had a severe or protracted anaphylaxis (e.g. required repeated doses of adrenaline or IV fluid resuscitation), OR
  • Have a history of severe/protracted anaphylaxis, OR
  • Have other concomitant illness (e.g. severe asthma, history of arrhythmia, systemic mastocytosis), OR
  • Live alone or are remote from medical care, OR
  • Present for medical care late in the evening.

True biphasic reactions are estimated to occur following 3-20% of anaphylactic reactions.

Adrenaline injector prescription and training

If there is a risk of re-exposure to allergens such as stings or foods, or if the cause of anaphylaxis is unknown (idiopathic) then prescribe and if possible dispense an adrenaline injector before discharge, pending specialist review. It is important to teach the patient how to use the adrenaline injector using a trainer device and provide them with an ASCIA Action Plan for Anaphylaxis which can be completed online and printed from the ASCIA website

Clinical immunology/allergy specialist referral

It is important that ALL patients who present with anaphylaxis are referrred to a clinical immunology/allergy specialist listed at will:.

  • Identify/confirm cause.
  • Educate about avoidance/prevention strategies and management of comorbidities.
  • Provide ASCIA Action Plan for Anaphylaxis - preparation for future reactions.
  • Initiate allergen immunotherapy where available (for some insect venoms).
  • Refer to other relevant health professionals as required (e.g. dietitian).

ASCIA anaphylaxis resources

Management of anaphylaxis in the community (including the home, schools and children’s education/care) is facilitated by regular training and the use of an ASCIA Action Plan for Anaphylaxis, which includes instructions that are consistent with these guidelines.

To access ASCIA Action Plans and other anaphylaxis resources, including e-training courses, go to

Documentation of episodes

Patients should be advised to document episodes of anaphylaxis, and the ASCIA allergic reactions event record can be used to collect this

This facilitates identification of avoidable causes (such as food, medication, herbal remedies, bites and stings, co-factors like exercise) in the 6-8 hours preceding the onset of symptoms.

Patient and carer support

Patients should be referred to patient and carer support organisations for information on daily management and support whilst they await clinical immunology/allergy specialist review.

(Video) Launch of the Acute Anaphylaxis Clinical Care Standard

Allergy & Anaphylaxis Australia Allergy New Zealand

Appendix A: Advanced Acute Management of Anaphylaxis

This additional information is intended for health professionals working in emergency departments, ambulance services, and rural or regional areas, who provide emergency care.

Supportive management (when skills and equipment available)

  • Monitor pulse, blood pressure, respiratory rate, pulse oximetry, conscious state.
  • Give high flow oxygen (6-8 L/min) and airway support if needed.
  • Supplemental oxygen should be given to all patients with respiratory distress, reduced conscious level and those requiring repeated doses of adrenaline.
  • Supplemental oxygen should be considered in patients who have asthma, other chronic respiratory disease, or cardiovascular disease.
  • Obtain intravenous (IV) access in adults and in hypotensive children.
  • If hypotensive:
    • Give intravenous normal saline (20 mL/kg rapidly under pressure), and repeat bolus if hypotension persists.
    • Consider additional wide bore (14 or 16 gauge for adults) intravenous access.

During severe anaphylaxis with hypotension, marked fluid extravasation into the tissues can occur: DO NOT FORGET FLUID RESUSCITATION.

Assess circulation to reduce risk of overtreatment

  • Monitor for signs of overtreatment (especially if respiratory distress or hypotension were absent initially) – including pulmonary oedema, hypertension.
  • In this setting (anaphylaxis) it is recommended that if possible a simple palpable systolic blood pressure (SBP) should be measured:
    • Attach a manual BP cuff of an appropriate size and find the brachial or radial pulse.
    • Determine the pressure at which this pulse disappears/reappears (the "palpable" systolic BP).
    • This is a reliable measure of initial severity and response to treatment
    • Measurement of palpable SBP may be more difficult in children.

Note: If a patient is nauseous, shaky, vomiting, or tachycardic but has a normal or elevated SBP, this may be adrenaline toxicity rather than worsening anaphylaxis.

Additional measures - IV adrenaline infusion

IV adrenaline infusions should only be given by, or in liaison with, an emergency medicine/critical care specialist.

If your centre has a protocol for IV adrenaline infusion for critical care, this should be utilised and titrated to response with close cardio-respiratory monitoring.

If there is not an established protocol for your centre, two protocols for IV adrenaline infusion are provided, one for pre-hospital settings and a second for emergency departments/tertiary hospital settings only.

It is important to note that the two infusion protocols have different concentrations and different rates of IV fluid infusion, resulting in the same initial rate of adrenaline infusion.

It is vital that IV adrenaline infusions should be used with the following equipment wherever possible:

  • Dedicated line.
  • Infusion pump.
  • Anti-reflux valves in intravenous line.

Additional measures - IV adrenaline infusion for pre-hospital settings

If there is inadequate response to IMI adrenaline or deterioration, start an intravenous adrenaline infusion. IV adrenaline infusions should only be given by, or in liaison with, an emergency medicine/critical care specialist.

The protocol for 1,000 mL normal saline is as follows:

  • Mix 1 mL of 1:1,000 adrenaline in 1,000 mL of normal saline.
  • Start infusion at ~5 mL/kg/hour (~0.1 microgram/kg/minute).
  • If you do not have an infusion pump, a standard giving set administers ~20 drops per mL; therefore, start at ~2 drops per second for an adult.
  • Titrate rate up or down according to response and side effects.
  • Monitor continuously – ECG and pulse oximetry and frequent non-invasive blood pressure measurements as a minimum to maximise benefit and minimise risk of overtreatment and adrenaline toxicity.


  • This protocol is intended for temporary use, when no infusion pump is available.
  • Most anaphylactic reactions settle with only 1 mg adrenaline in 1 litre.
  • Indefinite continuation of low concentration infusion increases risk of fluid overload.
  • Caution - Intravenous boluses of adrenaline are NOT recommended due to risk of cardiac ischaemia or arrhythmia UNLESS the patient is in cardiac arrest.

Additional measures: IV adrenaline infusion for emergency departments/ tertiary hospitals only

This infusion will facilitate a more rapid delivery through a peripheral line and should only be used in emergency departments and tertiary hospital settings.

The protocol for 100 mL normal saline is as follows:

(Video) Anaphylaxis Medical Management in 60 seconds

  • Mix 1 mL of 1:1,000 adrenaline in 100 mL normal saline.
    • Initial rate adjusted accordingly to 0.5 mL/kg/hour (~0.1 microgram/kg/minute).
    • Should only be given by infusion pump.
  • Monitor continuously – ECG and pulse oximetry and frequent non-invasive blood pressure measurements as a minimum to maximise benefit and minimise risk of overtreatment and adrenaline toxicity.

Additional measures to consider if IV adrenaline infusion is ineffective

For persistent hypotension/shock:

  • Give normal saline (maximum of 50mL/kg in first 30 minutes).
  • In patients with cardiogenic shock (especially if taking beta blockers) consider an intravenous glucagon bolus of:
    - 1-2mg in adults
    - 20-30 microgram/kg up to 1mg in children
    This may be repeated or followed by an infusion of 1mg/hour in adults.
  • In adults, selective vasoconstrictors metaraminol (2-10mg) or vasopressin (10-40 units) only after advice from an emergency medicine/critical care specialist. Beware of side effects including arrhythmias, severe hypotension and pulmonary oedema.

In children, metaraminol 10 micrograms/kg/dose can be used. Noradrenaline infusion may be used in the critical care setting, only with invasive blood pressure monitoring.

Advanced airway management

  • Oxygenation is more important than intubation.
  • Always call for help from the most experienced person available.
  • If airway support is required, first use the skills you are most familiar with (e.g. jaw thrust, Guedel or nasopharyngeal airway, bag-valve-mask with high flow oxygen attached). This will save most patients, even those with apparent airway swelling (these patients have often stopped breathing due to circulatory collapse rather than airway obstruction and can be adequately ventilated with basic life support procedures).
  • DO NOT make prolonged attempts at intubation - remember the patient is not getting any oxygen while you are intubating.

If unable to maintain an airway and the patient's oxygen saturations are falling, further approaches to the airway (e.g. cricothyrotomy) should be considered in accordance with established difficult airway management protocols. Specific training is required to perform these procedures.

Special situation: Overwhelming anaphylaxis (cardiac arrest)

Key points:

  • Massive vasodilatation and fluid extravasation.
  • Unlikely that IMI adrenaline will be absorbed in this situation due to poor peripheral circulation.
  • Even if absorbed, IMI adrenaline on its own may be insufficient to overcome vasodilatation and extravasation.
  • Need both IV adrenaline bolus (cardiac arrest protocol, 1 mg every 2-3 minutes) AND aggressive fluid resuscitation in addition to CPR (Normal Saline 20mL/kg stat, through a large bore IV under pressure, repeat if no response).
  • Do not give up too soon - this is a situation when prolonged CPR should be considered, because the patient arrested rapidly with previously normal tissue oxygenation, and has a potentially reversible cause.

Appendix B: Acknowledgements

A list of anaphylaxis references is available on the ASCIA

The information in these guidelines is consistent with the following publications:

These guidelines are also based on the following international guidelines:

© ASCIA 2023

Content updated January 2023

ASCIA is the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand.

ASCIA resources are based on published literature and expert review, however, they are not intended to replace medical advice. The content of ASCIA resources is not influenced by any commercial organisations.

For more information go to

(Video) Anaphylaxis in 3 minutes .. Anaphylactic Shock Management

To donate to allergy and immunology research go to


What are the guidelines for treatment of anaphylaxis? ›

Adults should receive 1 to 2 liters of normal saline at the most rapid flow rate possible in the first minutes of treatment. Large volumes of fluid (eg, up to 7 liters) may be required. Children should receive normal saline in boluses of 20 mL/kg, each over 5 to 10 minutes, and repeated, as needed.

What is the single best answer with regards to anaphylaxis? ›

Which of the following is the single best statement with regard to anaphylaxis? The allergic reaction always causes hives.

How do you manage anaphylaxis in ACLS? ›

Management of Anaphylactic Shock:

The most important intervention for the treatment of anaphylactic shock is the use of IM epinephrine. Pediatric dosing for IM epinephrine, using concentration of 1:1,000, is 0.01 mg/kg intramuscular (max dose 0.5 mg). This may be repeated every 5-15 min. as needed if symptoms persist.

What are the principles of emergency management for anaphylaxis? ›

Immediate actions for anaphylaxis

Give oxygen (if available). Phone ambulance - 000 (AU) or 111 (NZ) to transport patient if not already in a hospital setting. Phone family/emergency contact. Further adrenaline may be given if no response after 5 minutes.

What are the five steps given for anaphylaxis action? ›

Treatment for anaphylaxis
  • Lay the person flat (do not allow them to stand or walk).
  • Give adrenaline autoinjector.
  • Phone ambulance – dial triple zero (000).
  • Phone family/emergency contact.
  • Further adrenaline doses may be given if no response after 5 minutes.
May 14, 2021

What is the most important treatment in anaphylaxis? ›

Adrenaline: The most important drug in the acute therapy of anaphylaxis is adrenaline (epinephrine).

How do you treat anaphylaxis without an EpiPen? ›

Have the person lie face up and be still. Loosen tight clothing and cover the person with a blanket. Don't give the person anything to drink. If there's vomiting or bleeding from the mouth, turn the person to the side to prevent choking.

What to do if someone goes into anaphylactic shock without EpiPen? ›

If you believe someone near you is suffering from anaphylactic shock, call 911. Do this first if the person doesn't have an EpiPen. Perform CPR. If the person suffering the allergic reaction does not have an EpiPen and loses consciousness, you may have to perform CPR.

What are the three most significant indicators of anaphylactic shock? ›

About anaphylaxis

Signs of anaphylaxis include: itchy skin or a raised, red skin rash. swollen eyes, lips, hands and feet. feeling lightheaded or faint.

What is the priority nursing intervention for a patient experiencing anaphylaxis? ›

Nursing Problem Priorities

Monitor and assess breathing. Monitor and assess circulation. Administer epinephrine promptly. Provide fluid resuscitation as needed.

What is an anaphylaxis action plan? ›

ASCIA Action Plans for Anaphylaxis provide instructions for first aid treatment of anaphylaxis, to be delivered by people without any special medical training or equipment, apart from access to an adrenaline autoinjector.

What is an anaphylaxis emergency plan? ›

An anaphylaxis emergency plan lists a person's allergies, the signs and symptoms to watch for, and the emergency procedure to follow in case of a reaction. It's important to share this form with your child's school and caregivers, and to review it with your child, depending on their age.

What is anaphylaxis initial emergency treatment by nurses? ›

Epinephrine is the first line treatment for anaphylaxis and there is no known equivalent substitute. Prompt intramuscular injection of epinephrine should not be delayed by taking the time to administer antihistamines, and thus, these medications are not recommended in the initial emergency management of anaphylaxis.

What 3 criteria aid with diagnosis recognition of anaphylaxis? ›

Anaphylaxis is likely when all of the following 3 criteria are met: Sudden onset and rapid progression of symptoms. The person will feel and look unwell. Most reactions occur over several minutes.

What 4 systems are involved in anaphylaxis? ›

Anaphylaxis is an acute multiorgan system reaction. The most common organ systems involved include the cutaneous, respiratory, cardiovascular, and gastrointestinal (GI) systems.

Why is it important to treat anaphylaxis immediately? ›

Anaphylactic shock can be life-threatening. If you notice anaphylaxis symptoms, inject yourself with epinephrine right away. Then call 911 or get to the emergency room. Prompt anaphylaxis treatment can save your life.

How would you manage the associated risk of anaphylaxis provide at least three 3 steps? ›

Important steps for long-term risk minimisation include avoidance of triggers, prescription of an adrenaline autoinjector, maintenance of a personalised emergency action plan for anaphylaxis, education for patients and families and regular review to optimise management.

Can Benadryl help if no EpiPen? ›

FACT: NO, epinephrine is the first-line treatment for anaphylaxis. Antihistamines, like Benadryl®, do not reverse the symptoms of anaphylaxis and should not be used instead of epinephrine.

What is the difference between anaphylaxis and anaphylactic shock? ›

Anaphylaxis is a severe, life-threatening, generalized or systemic rapid-onset hypersensitivity reaction (allergic or nonallergic). Anaphylactic shock is a severe rapidly progressing anaphylactic reaction (anaphylaxis) resulting in a life-threatening drop in blood pressure.

How much Benadryl should I take for anaphylaxis? ›

Administer the antihistamine diphenhydramine (Benadryl, adults: 25 to 50 mg; children: 1 to 2 mg per kg), usually given parenterally. If anaphylaxis is caused by an injection, administer aqueous epinephrine, 0.15 to 0.3 mL, into injection site to inhibit further absorption of the injected substance.

Can anaphylaxis resolve without epinephrine? ›

Fatal outcomes due to anaphylaxis are rare,25, 26 and around 80% of reactions resolve without (or despite no treatment with) adrenaline. However, severe reactions cannot be predicted,1 thus all anaphylaxis reactions must be treated as potentially life-threatening.

What is the hallmark of anaphylaxis? ›

The hallmark of anaphylaxis is the precipitate onset of multisystem dysfunction with respiratory, cardiovascular, gastrointestinal, and or neurological system involvement.

What is the first line for anaphylactic shock? ›

Anaphylaxis needs emergency first aid. The first line treatment is injection of adrenaline (epinephrine) into the outer mid-thigh. Do not allow the person to stand or walk. Give further doses of adrenaline if there is no response after 5 minutes.

Which 3 symptom is a common anaphylactic reaction? ›

Symptoms of anaphylaxis

feeling lightheaded or faint. breathing difficulties – such as fast, shallow breathing. wheezing. a fast heartbeat.

What is the first action the nurse should take when a patient is having an anaphylactic reaction to an IV medication? ›

The FIRST step the nurse should take is to immediately remove the allergen. This would be stopping the medication, and then call a rapid response. The nurse should maintain the airway and start CPR (if needed) until help arrives.

What intervention is a priority for the nurse? ›

The first-level priority problems are health issues that are life-threatening and require immediate attention. These are health problems associated with ABCs; airway, breathing, and circulation, such as establishing an airway, supporting breathing, and addressing sudden perfusion and cardiac issues.

What is the emergency treatment of anaphylaxis in adults concise guidance? ›

Adrenaline is the most important drug for the treatment of an anaphylactic reaction. Failure to inject adrenaline promptly increases the risk of death. Adverse effects of adrenaline are extremely rare when the correct doses are injected intramuscularly.


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Name: Nicola Considine CPA

Birthday: 1993-02-26

Address: 3809 Clinton Inlet, East Aleisha, UT 46318-2392

Phone: +2681424145499

Job: Government Technician

Hobby: Calligraphy, Lego building, Worldbuilding, Shooting, Bird watching, Shopping, Cooking

Introduction: My name is Nicola Considine CPA, I am a determined, witty, powerful, brainy, open, smiling, proud person who loves writing and wants to share my knowledge and understanding with you.